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Protocol X has always been about pushing the boundaries of healthy longevity, and its third evolution – Protocol X V3 –  raises the bar even higher with our most advanced formula yet. It delivers double the creatine and introduces glycine and Ligno Cordyceps to boost energy, recovery and resilience. 

Thoughtfully developed and rigorously vetted by longevity science experts, Protocol X V3 is an all-in-one, high-performance, holistic protocol that can help you live not just longer, but better.

The Ultimate Goal: Living Well 

True longevity is about thriving, not just surviving. With global populations living longer than ever, staying strong, mentally sharp, and resilient is no longer optional – it’s essential. We need to plan ahead to stay strong, maintain energy, mental clarity, and physical resilience.

The World Health Organization projects a rise in the global population aged 60 and older from 1.1 billion in 2023 to 1.4 billion by 2030. High-functioning health isn’t just about quality of life – it’s about maintaining independence, energy, and even long-term financial well-being.

How Do We Age Well?

Genetics may set the stage, but the choices we make every day play a role in shaping how we age. Living fully, with energy, clarity, and resilience, starts with a few simple but powerful science-backed habits:

• Move your body: Exercise preserves strength, endurance, and mobility.
  
• Exercise your mind: Challenge your brain to keep cognition sharp.
  
• Eat well: Whole foods provide the nutrients your cells need to thrive.
  
• Prioritize sleep: Deep, restorative sleep fuels recovery, hormone balance, and general vitality.
  
• Stay socially connected: Friendships, community, and acts of kindness nurture emotional resilience and purpose.
  
• Support with science: Even a healthy lifestyle can benefit from targeted supplementation.

High-Performance Aging: Protocol X® V3 Supports Energy, Recovery, and Resilience

Targeted supplementation can make a real difference to supporting living better for longer. Emerging research shows that supporting cellular energy, recovery, and cognitive function is key.

From Protocol X…

The foundational formula brought together 20+ vetted ingredients that support your healthspan holistically in an all-in-one daily supplement. 

See: The Science Behind Longevity: Key Ingredients in Our New Supplement.

…To Protocol X V3: What’s changed? 

The upgraded formula eliminates redundancies and harnesses the latest verified longevity science, now supporting 13 vital body functions vs 11 before. 

• It retains the original proven essentials, including Ca AKG, Taurine, Ergothioneine, Vegan Collagen Booster VC-H1®, Hyaluronic Acid, Vitamin D3 (1000 IU, now sourced from lichen), and Sialic Acid
• And adds Glycine and Cordyceps for enhanced longevity and high-performance benefits.

Let’s delve deeper into V3. 

The Holistic Longevity Advantage

Protocol X V3 supports the full spectrum of high-performance longevity: energy, recovery, cognition, and resilience.

Energy from the Inside Out: Creatine + NMN

Creatine for Muscle, Brain, and Longevity

Creatine isn’t just for athletes. Research shows it also supports muscle preservation, cognitive performance, mental health and cellular energy, making it a crucial component of longevity. 

Protocol X V3 upgrade: Creatine Monohydrate 1000 mg → 2000 mg. Doubled for improved muscle strength and recovery.

Explore its benefits in Creatine for Strength, Brain Health & Longevity: A Scientific Analysis.

NMN and NAD+: Cellular Energy and Anti-Aging

NMN is a precursor to NAD+, a molecule essential for cellular energy, DNA repair, and mitochondrial function. Maintaining NAD+ levels supports both physical and mental vitality. 

Protocol X V3 upgrade: NMN 250 mg → 400 mg. Higher dose for enhanced NAD+ and cellular energy support.

Learn more in Xandro NMN: Can It Really Boost Cellular Energy and Anti-Ageing? and What Is NMN? Safe Dosage, Benefits & Best Supplements Explained.

Why it matters: Creatine and NMN together fuel the body and brain, ensuring you can perform, recover, and thrive – no matter your age.

New Additions: Glycine + Cordyceps

Glycine 500 mg: Sleep, Collagen, and Recovery Support

Glycine is a simple amino acid with outsized effects. Found in meat, fish, dairy and legumes, but for most people – and especially as we age – that’s often not enough to r it’s often not enough to meet longevity and recovery needs. 

Glycine helps support autophagy¹ (cell renewal through natural clearing of damaged cells), restorative sleep², stronger cellular recovery³, longevity gene pathways and collagen production, all essential for recovery and longevity. 

Learn more in What is Glycine Good For? Benefits, Uses and Side Effects.

Cordyceps 400 mg: Endurance and Stress Adaptation

Ligno Cordyceps mushroom, a natural adaptogen, helps enhance oxygen utilization (VO₂ max), endurance, immune resilience⁴, and ATP production. It helps the body adapt to stress while maintaining high performance. 

Discover its benefits in Best Supplements for the Immune System and Age-Related Illnesses.

Why it matters: Glycine and Cordyceps together support deep recovery, better sleep, increased resilience, collagen and joint support, endurance, stress adaptation – helping you sustain energy and performance over time.

Who Benefits from Protocol X V3?

It’s designed for anyone committed to living better as they age:

• Active Agers (40s–60s): Supports NAD+ levels, memory, metabolism, and skin health, helping maintain vitality and cognitive clarity.
• Athletes and Biohackers: Enhances muscle performance, energy, endurance, and recovery, supporting high-intensity training or daily active living.
• Longevity Lifestyle Users: Promotes deep cellular repair, immune resilience, collagen pathways, and restorative sleep, key pillars for long-term health and wellness.

How to Integrate Protocol X V3 Into Your Routine

Taking it is simple: mix one tasty citrus-flavoured sachet in a glass of water or favorite drink once a day before food. 

Confused about integrating this all-in-one supplement with your existing supplementation regime? How to Stack Protocol X with Other Longevity Supplements gives you the low-down. 

For more on Protocol X and longevity science, read Unlocking Longevity: How Our New Supplement Supports a Longer, Healthier Life.

Live Better, Stronger, Smarter 

High-performance longevity isn’t measured by years alone – it’s about energy, resilience, and quality of life. Whether your goals are stronger muscles, sharper cognition, faster recovery, or all of the above, Protocol X V3 is designed to help you stay vital, perform stronger, recover faster, and sleep better—today and for decades to come.

Discover Protocol V3 and optimize your high-performance longevity today.

FAQ

Q: What is Protocol X V3?
A: Protocol X V3 is Xandro’s third-generation, science-backed, all-in-one longevity supplement designed to support 13 body functions, including energy, recovery, cognitive clarity, and resilience. It combines 20+ key ingredients, including Creatine, NMN, Glycine, and Ligno Cordyceps, into a holistic, high-performance formula.

Q: How is Protocol X V3 formulated differently from other longevity supplements?
A: Unlike single-ingredient products, Protocol X V3 is a third-generation, science-backed formula that combines multiple complementary ingredients, carefully dosed and vetted to support multiple pillars of healthy aging simultaneously.

Q: How is Protocol X V3 different from previous versions?
A: This third evolution includes higher doses of Creatine for enhanced muscle and cellular energy, plus the addition of Glycine for sleep and cellular repair, and Ligno Cordyceps to boost endurance, mitochondrial function, and immune resilience.

Q: How does Creatine support both muscles and the brain?
A: Creatine isn’t just for athletes. It helps regenerate cellular energy (ATP) in muscles and neurons, improving strength, recovery, and cognitive clarity, especially as we age. Protocol X V3 includes an increased Creatine dose to benefit both body and mind. 

Q: Can NMN or NAD+ supplements actually slow aging?
A: Research suggests that NMN supplementation boosts NAD+ levels, supporting cellular energy, DNA repair, and mitochondrial health – key factors linked to healthier aging and longevity. Protocol X V3 provides a clinically supported NMN dose for these benefits. .

Q: How does Glycine improve sleep and recovery?
A: Glycine is an amino acid that supports deeper, more restorative sleep, cellular repair and autophagy – processes critical for longevity and tissue recovery. Its inclusion in Protocol X V3 strengthens recovery and overall resilience. 

Q: What is Cordyceps good for?
A: Ligno Cordyceps is a mushroom extract that enhances endurance, mitochondrial function, and oxygen utilization (VO₂ max). It also supports immunity and overall energy, making it a key ingredient in longevity-focused supplements like Protocol X® V3. 

Q: Who should take Protocol X V3?
A: Protocol X V3 is designed for adults seeking high-performance longevity support, particularly those who want to maintain energy, recovery, cognitive clarity, and overall resilience as they age.

Q: Can I take Protocol X V3 with other supplements?
A: Yes, but it’s always best to check with a healthcare professional to ensure compatibility with your current supplement or medication routine. Read How to Stack Protocol X with Other Longevity Supplements.

Q:  How long before I see results with Protocol X V3?
A: Results can vary depending on lifestyle, diet, and activity levels. Many users report improved energy and recovery within a few weeks, while long-term benefits, like enhanced resilience and cognitive support, develop over consistent use.

Q: Is Protocol X V3 backed by science?
A: Yes. Every ingredient in Protocol X V3 is selected based on credible research and expert vetting. The formula reflects the latest findings in longevity, performance, and cellular health.

Q: Are there any side effects of taking Protocol X V3?
A: Protocol X V3 uses clinically studied ingredients at safe, effective doses. Most people tolerate it well, but anyone with medical conditions or on medications should consult a healthcare professional before starting any supplement.

Q: Can I take Protocol X V3 if I don’t exercise regularly?
A: Yes. While Creatine and Cordyceps are often associated with athletic performance, their cellular energy and endurance benefits support anyone looking to maintain vitality, cognitive clarity, and recovery—even without intense exercise.

Q: What makes Protocol X® V3 a high-performance longevity supplement?
A: It’s the combination of ingredients, precise dosing, and ongoing scientific vetting. From energy and recovery to cognition and resilience, Protocol X V3 addresses the holistic needs of adults seeking to live longer, stronger, and healthier.

Scientific References

1. de Paz-Lugo, P., Lupiáñez, J.A. & Meléndez-Hevia, E (2018). High glycine concentration increases collagen synthesis by articular chondrocytes in vitro: acute glycine deficiency could be an important cause of osteoarthritis. Amino Acids 50, 1357–1365 (2018). https://doi.org/10.1007/s00726-018-2611-x
2. Inagawa, K., et al. (2006). Subjective effects of glycine ingestion before bedtime on sleep quality. Sleep Biol Rhythms, 4(1), 75–77. https://doi.org/10.1111/j.1479-8425.2006.00193.x
3. Adiv A. Johnson, Trinna L. Cuellar (2023). Glycine and aging: Evidence and mechanisms, Ageing Research Reviews, Volume 87, 2023, https://doi.org/10.1016/j.arr.2023.101922
4. Gitishree Das, et al. A (2021). Cordyceps spp.: Review on Its Immune-Stimulatory and Other Biological Potentials. Front. Pharmacol. https://doi.org/10.3389/fphar.2020.602364