What is Spermidine?

Spermidine is a polyamine compound, containing two or more primary amino groups.

It is a naturally occurring molecule that plays a pivotal role in cellular energy production.

☑️ Prolong Hair Growth Phase

☑️ Fasting Induced Benefits

☑️ Cognitive Protection

What makes Xandro Lab Spermidine better?

1. Highest concentration of 10 mg per capsule.
2. Pure Spermidine, highest purity at above 99%.
   
   

Did you know?

• Spermidine can help with promoting stronger hair and nail growth.
• In humans, spermidine levels decline with aging, and there is a suggestion that this decline might be linked to age-related health deterioration.
• Spermidine is found in good concentrations in many foods like shitake mushrooms and fermented products like miso.

Why supplement with Spermidine?

As we age, our cellular health inevitably declines.

• By stimulating autophagy, it supports the natural rejuvenation of our cells, defending against the effects of aging and oxidative stress.
• Backed by scientific research, Spermidine plays a critical role in healthy aging and extending healthy hair growth.

Scientific Evidence 

1) In a study involving older adults, three months of Spermidine supplementation showed improvements in cognitive performance compared to the group with lower Spermidine intake. In contrast, the group which had a lower spermidine intake showed consistent or declining cognitive performance¹.

2) Spermidine supplementation can extend the hair growth phase, offering potential benefits for individuals seeking good hair health. In a double-blinded, randomized, placebo-controlled trial, the spermidine group experienced significant increase of over 50% in the number of active hair follicles (anagen hair bulbs) after 90 days, while the placebo group experienced a significant decrease of approximately 20%².

3) In human epidemiological studies, higher dietary polyamine uptake (i.e. Spermidine) has been correlated with reduced cardiovascular mortality³.

Directions of use

• Take 1-2 capsules daily with food, preferably in the morning.
• If you are pregnant, nursing, or have a known medical condition, consult a physician before use.

☑️ 60 capsules

☑️ 10mg per capsule

☑️ Manufactured in a GMP-Certified Facility in Singapore

☑️ Third-party lab tested for purity

References: 

1. Schwarz C, Benson GS, Horn N, Wurdack K, Grittner U, Schilling R, Märschenz S, Köbe T, Hofer SJ, Magnes C, Stekovic S, Eisenberg T, Sigrist SJ, Schmitz D, Wirth M, Madeo F, Flöel A. Effects of Spermidine Supplementation on Cognition and Biomarkers in Older Adults With Subjective Cognitive Decline: A Randomized Clinical Trial. JAMA Netw Open. 2022 May 2;5(5):e2213875. doi: 10.1001/jamanetworkopen.2022.13875. PMID: 35616942; PMCID: PMC9136623.
2. Rinaldi F, Marzani B, Pinto D, Ramot Y. A spermidine-based nutritional supplement prolongs the anagen phase of hair follicles in humans: a randomized, placebo-controlled, double-blind study. Dermatol Pract Concept. 2017 Oct 31;7(4):17-21. doi: 10.5826/dpc.0704a05. PMID: 29214104; PMCID: PMC5718121.
3. Han S, Qian M, Zhang N, Zhang R, Liu M, Wang J, Li F, Zheng L, Sun Z. The Association of Dietary Polyamines with Mortality and the Risk of Cardiovascular Disease: A Prospective Study in UK Biobank. Nutrients. 2024 Dec 16;16(24):4335. doi: 10.3390/nu16244335. PMID: 39770955; PMCID: PMC11678356.