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How Protocol X Boosts Your Longevity

Have you ever thought about what’s the best supplement for anti-aging? Well, Xandro’s here to help.

Our newest longevity supplement is packed full of longevity ingredients backed by health science and clinical trials, making it possibly a great addition to your longevity supplement stack.

It’s called Protocol X and it’s a longevity mix full of scientifically backed research! You can learn more about our Protocol X supplement benefits in our previous article, but in this blog, we will be going over each ingredient.

Further Reading: Longevity Pathways

Head there now:

• Key Ingredients in Protocol X
  • Quercetin
  • Sialic Acid
  • Phosphotidylcholine
  • Vegan Collagen Booster VC-H1®
  • CaAKG
  • Taurine
  • Ergothioneine
  • Vitamin C
  • Vitamin D3
  • CoQ10
  • TMG
  • Spermidine
  • Creatine
  • Whole Antioxidant Complex
  • Sodium Hyaluronate
  • NMN
  • Citrusvel® Citrus Bioflavonoids Complex
• Who Should Take Protocol X?
• End Note

Key Ingredients in Protocol X

So, what’s in Protocol X? This longevity supplement contains a range of anti-aging ingredients, but don’t just take our word for it, let’s dive into the scientific research supporting each ingredient!

Quercetin – 200mg

Quercetin dihydrate is a plant compound (polyphenol) with strong antioxidant properties, known for its protective effects against aging. It is commonly found in fruits and vegetables and has been part of human diets for centuries, although the human body cannot make it. Quercetin dihydrate is a more stable and soluble form of quercetin.

For those interested in longevity, quercetin dihydrate offers several health benefits:

1. Antioxidant: Protects cells from damage by scavenging free radicals, reducing oxidative stress.
2. Anti-inflammatory: Lowers inflammation by preventing inflammatory cytokines and enzymes.
3. Cardiovascular Health: Lowers blood pressure, reduces cholesterol and improves blood vessel function.
4. Anti-carcinogenic: Prevents cancer cell growth and promotes the death of cancer cells.
5. Anti-diabetic: Helps manage blood sugar levels and prevent diabetes-related complications.
6. Neuroprotection: Crosses the blood-brain barrier to protect against neurodegenerative diseases.

Sialic Acid – 25mg

Sialic acid is a key molecule with numerous health benefits, especially for those interested in longevity. Here's why we’ve added it to Protocol X:

1. Brain Health: Sialic acid is crucial for brain development and function. It enhances cognitive performance, supports neurodevelopment and is linked to better learning and memory. It may also help prevent or manage neurodegenerative diseases like Alzheimer's.
2. Immune Support: Sialic acid helps regulate the immune system and prevents infections, such as influenza, by acting as a protective barrier on cell surfaces.
3. Cardiovascular Health: It influences blood coagulation and cholesterol levels, contributing to heart health.
4. Diabetes Management: Sialic acid levels are linked to diabetes and its complications, suggesting it may help manage the disease.
5. Metabolic Stability: It affects the lifespan and stability of glycoproteins in the bloodstream, which is important for overall metabolic health.

Phosphotidylcholine – 100mg

Phosphatidylcholine (PC) is a vital phospholipid, or fatty acid, that plays a key role in maintaining cell membrane health and supporting overall bodily functions. Here’s why we added it to our longevity supplement:

1. Cellular Health: PC improves cell metabolism by allowing nutrients to enter cells and waste to exit, which is important for maintaining healthy cells and overall well-being. PC levels decrease with age and exposure to toxins, making supplementation important.
2. Brain Health: Supports brain function and may help with memory loss associated with aging. It contributes to the production of acetylcholine, a neurotransmitter important for learning and memory.
3. Mitochondrial Function: PC is abundant in mitochondrial membranes, supporting energy production. This helps improve energy levels and protects against cardiovascular diseases, metabolic dysfunction, diabetes and neurodegenerative diseases.
4. Heart Health: Contrary to past misconceptions, PC supports heart health. It is different from lecithin and is crucial for cardiovascular function.
5. Liver and Lung Function: PC is used in bile production, needed for fat digestion and liver health. It also acts as a lung surfactant, improving respiratory function and providing protection during viral seasons.
6. Gut Health: PC is vital for the intestinal mucosa, protecting the gut lining. It may help with conditions like ulcerative colitis by reducing inflammation and supporting gut health.

Vegan Collagen Booster VC-H1® – 2000mg

VC-H1® collagen is the first vegetable collagen recognised worldwise, but how can it benefit your longevity?

1. Improves Sleep and Mood: Collagen contains glycine, an amino acid that helps lower body temperature for better sleep and boosts mood by increasing serotonin levels.
2. Boosts Brain Health: Glycine in collagen can improve cognitive functions, support memory, and help manage mental disorders like depression and neurodegenerative diseases.
3. Provides Antioxidants and Protects Against Asthma: Collagen helps increase glutathione levels, a crucial antioxidant that protects against oxidative stress, cancer, heart disease and respiratory issues like asthma.
4. Stabilises Blood Sugar and Supports Heart Health: Glycine in collagen can regulate blood sugar and insulin levels, helping to prevent obesity and improve heart health.
5. Supports Gut Health: Collagen helps maintain and repair the gut lining, beneficial for conditions like leaky gut syndrome and irritable bowel syndrome (IBS).
6. Prevents Tumour Growth and Cancer: Collagen has anti-inflammatory properties that may help prevent cancer and support longevity in cancer patients.
7. Improves Joint Health: Collagen supports joint and cartilage health, reduces joint pain and helps prevent osteoporosis, especially in post-menopausal women.

Further Reading: Common Ingredients in Beauty Supplements

CaAKG – 500mg

Calcium Alpha-Ketoglutarate (Ca-AKG) is a supplement that could benefit those interested in longevity. We have an individual CaAKG supplement and have written multiple articles on this longevity ingredient, so be sure to check out our blog. Here’s why we’ve added it to Protocol X:

1. Energy and Protein Synthesis: AKG is crucial for energy production and protein synthesis in cells.
2. Amino Acid Formation: It helps form essential amino acids like glutamine and arginine.
3. Antioxidant Properties: Acts as an antioxidative agent, potentially benefiting memory and neurological health.
4. Tumour Prevention: May prevent tumour growth by inducing hypoxia.
5. Gene Regulation: Influences gene expression and cell signalling related to growth and aging.
6. Inflammation Reduction: Suppresses chronic inflammation, improving frailty, hair loss, and body weight.
7. Muscle Protection: Prevents muscle protein breakdown.
8. Bone Health: Increases levels of compounds important for bone health, such as type-I collagen.
9. Cardioprotection: Benefits heart cells during surgery.
10. Anti-Cancer Potential: Regulates pathways involved in cancer, potentially reversing metabolic responses in cancer cells.

Further Reading: The Benefits of Calcium AKG for Athletes

Taurine – 1000mg

Taurine is a supplement that has shown promising benefits for longevity and overall health. Research in mice and monkeys suggests that taurine can help you live a longer, healthier life. Here’s why you might consider taking it:

1. Healthier Aging: Mice supplemented with taurine were healthier at age 2 (equivalent to 60 in human years), showing improvements in almost every health parameter.
2. Weight and Energy: It helps reduce age-related weight gain, increases energy expenditure and prevents weight gain in monkeys.
3. Bone and Muscle Health: Taurine increases bone mass, muscle endurance and strength.
4. Mental Health: It reduces depression-like and anxious behaviours.
5. Metabolic Health: Taurine reduces insulin resistance and fasting blood glucose levels.
6. Immune System: It helps you maintain a more youthful immune system.
7. Cellular Health: At the cellular level, taurine decreases harmful ‘zombie cells,’ increases stem cell presence for tissue repair, improves mitochondrial performance, reduces DNA damage and improves cells’ nutrient sensing.

Ergothioneine – 3mg

Ergothioneine (ERGO) is a powerful antioxidant and anti-inflammatory amino acid found abundantly in mushrooms that may help you live a longer, healthier life. Here’s why we’ve added it to Protocol X:

1. Chronic Disease Prevention: ERGO has potential to prevent or mitigate chronic diseases of aging.
2. Anti-Aging Properties: ERGO has anti-aging, anti-inflammatory and anti-neurodegenerative effects.
3. Superior Antioxidant: It is more stable and effective at scavenging free radicals compared to other antioxidants like glutathione and vitamin E.
4. Senescent Cell Clearance: ERGO helps clear senescent cells, which can improve lifespan and health span by alleviating various aging-related issues.
5. Broad Health Benefits: It may help with conditions like Parkinson’s disease, cognitive impairment, depression, cataracts, cardiovascular disease, liver and kidney diseases, diabetes complications and even some cancers.

Vitamin C – 400mg

Vitamin C, also known as ascorbic acid, is an essential antioxidant that has many benefits for longevity, including:

1. Cell Protection: Vitamin C is a powerful antioxidant that protects your cells from damage caused by free radicals, helping to fend off aging and chronic diseases.
2. Immune Support: Vitamin C boosts your immune system, helps regulate inflammation and can shorten the duration of colds.
3. Cognitive Benefits: For older adults, it enhances cognitive functions such as memory and decision-making and may help prevent cataracts.
4. Skin Health: It improves skin hydration, stimulates collagen production and reduces wrinkles, making it beneficial for maintaining youthful skin.
5. Gut Health: It may increase the production of short-chain fatty acids, supporting the gut-brain connection and protecting the intestinal barrier. It can also help balance gut bacteria, which may benefit those with inflammatory bowel diseases such as Crohn’s disease and ulcerative colitis.
6. Digestive Health: Essential for digestion, vitamin C supports healthy gums and teeth and enhances the absorption of iron from food.

Further Reading: Does Chewing Vitamin C Reduce Its Effect?

Vitamin D3 – 25mg

Vitamin D is crucial for overall health and longevity, which is why we’ve added it to Protocol X. Here’s how it can help extend your health span:

1. Bone Health: Vitamin D helps your body absorb calcium, which is essential for strong bones and may help prevent conditions like osteoporosis and arthritis.
2. Immune Support: It supports immune function and may lower the risk of certain diseases, including colon cancer and inflammatory bowel diseases.
3. Hormonal Balance: Vitamin D helps regulate hormones, including estrogen and progesterone and supports insulin function, which can aid in managing conditions like Polycystic Ovary Syndrome (PCOS) and diabetes.
4. Digestive Health: Although more research is needed, vitamin D might help balance the gastrointestinal tract and reduce inflammation.
5. Brain Health: It plays a role in brain function, helping with mood regulation, memory, and cognitive functions. Low levels of vitamin D are linked to poorer brain health.

CoQ10 – 30mg

Coenzyme Q10 (CoQ10) is a vital antioxidant that supports cellular energy production and overall health. CoQ10 levels naturally decline with age, so supplements can help restore these levels. Here's why it’s beneficial for longevity:

1. Energy and Vitality: CoQ10 helps convert food into energy, boosting your overall energy levels and improving physical performance.
2. Cardiovascular Health: It supports heart health by reducing inflammation, improving blood sugar regulation and protecting against oxidative stress. Studies suggest it may lower the risk of heart-related issues.
3. Brain Health: CoQ10 levels decrease with age, and low levels are linked to higher risks of dementia, Alzheimer’s and Parkinson’s disease. Supplementing with CoQ10 may improve cognitive function and slow cognitive decline.
4. Anti-Aging Benefits: It protects cells from damage by neutralizing free radicals, which can help reduce wrinkles, prevent macular degeneration and contribute to overall anti-aging.
5. Immune Support: CoQ10 is needed for a healthy immune system, as it helps cells involved in immunity function efficiently.

Further Reading: The Power of CoQ10 Supplements

TMG – 200mg

Trimethylglycine (TMG), also known as betaine, is a form of the amino acid glycine with three methyl groups attached. TMG functions as a methyl donor, supporting various biological processes. Why did we add it to our new longevity supplement?

1. DNA Methylation: TMG supports DNA methylation, a process vital for gene expression and cellular function, which impacts epigenetic aging. As we age, our methyl pools deplete, contributing to age-related diseases, so adding TMG to Protocol X helps replenish these pools.
2. Lowers Homocysteine Levels: High homocysteine levels are a risk factor for heart disease and TMG converts homocysteine into methionine, potentially reducing this risk, especially in individuals with MTHFR gene mutations.
3. Improves Athletic Performance: TMG may improve oxygen uptake and power output during exercise. It may also reduce fatigue and improve endurance, and it also benefits muscle mass and strength in resistance training.
4. Potential Cancer Role: Some studies suggest higher TMG intake might reduce cancer risk and mortality, though more research is needed.
5. Supports Depression Management: TMG may increase S-adenosyl methionine (SAMe) levels, which help produce neurotransmitters linked to mood regulation.
6. Improves Cognitive Function: Studies suggest TMG might improve memory and response time, particularly in seniors.

Spermidine 3HCL – 1mg

Spermidine is a compound that activates autophagy, mimicking the effects of intermittent fasting and calorie restriction. It has a range of longevity benefits, hence why we’ve added it to our new supplement.

1. Autophagy Activation: Helps in the removal of old cells and supports cellular renewal, enhancing metabolism and energy.
2. Weight Management: Mimics intermittent fasting, helping with weight loss and improving insulin resistance.
3. Energy Booster: Increases daily energy levels and regulates lipid metabolism for better cellular energy production.
4. Supports Hair and Nails: Benefits hair and nail follicle health, promoting stronger hair and nails.
5. Heart, Cognition and Liver Health: May reduce blood pressure, lower the risk of cardiovascular disease and provide neuroprotective benefits against diseases like Alzheimer’s.
6. Hormone Balance: Increases reproductive hormones, such as testosterone in men under 50, enhancing sexual performance.
7. Immune Function Support: Boosts immunity by enhancing cellular responses to infections and improving the memory of immune cells.

Further Reading: Answering Spermidine FAQs

Creatine Monohydrate – 1000mg

Creatine is a naturally occurring compound found in skeletal muscle that helps produce adenosine triphosphate (ATP), providing energy for muscles. It’s one of the safest supplements and one of the most studied, but here’s why we’ve added it to Protocol X:

1. Cognitive Benefits: May improve short-term memory, intelligence, reasoning skills and study efficiency, especially in those who don't eat meat. It also improves the energy supply to the brain.
2. Muscle Health: Improves exercise capacity, muscle strength and recovery, leading to greater lean mass. It also helps muscles hold more water, making them look fuller and stronger.

Whole Antioxidant Complex – 1000mg

Antioxidants are key to slowing the aging process by neutralizing free radicals, unstable molecules that damage cells and lead to various health issues like heart disease, cancer and neurodegenerative conditions. Here’s why we included them in Protocol X:

1. Prevents Damage: Neutralise free radicals that damage cells, slowing aging.
2. Heart Health: Improves heart health by potentially protecting against cardiovascular disease.
3. Anti-Inflammatory: Helps prevent inflammation related to heart disease, diabetes and cancer.
4. Exercise Performance: Improves performance and endurance and aids muscle recovery. Can also boost metabolism and help increase fat burning, helping with weight loss.
5. Anti-Cancer Properties: May slow early tumour growth, particularly in liver and prostate cancers.
6. Brain Health: Protects against Alzheimer's and Parkinson's by reducing oxidative damage and supporting brain cell survival.
7. Digestive Health: Supports the gut microbiome and digestive health through prebiotic effects and fibre content.
8. Boost skin health: Preserves collagen and combat skin aging from sun exposure, pollution and stress.

Further Reading: All About Pomegranate As A Longevity Supplement

Sodium Hyaluronate – 50mg

Sodium hyaluronate is the salt form of hyaluronic acid with a smaller molecular structure for better stability and deeper skin penetration. Here’s why we added it to Protocol X for longevity:

1. Skin Health: Provides intense hydration, reduces wrinkles, improves skin suppleness and elasticity, and enhances skin radiance. Levels decline with age (a 70-year-old has 75 per cent less than a 19-year-old), so supplementation helps maintain youthful skin.
2. Joint Health: Enhances joint health by supporting cartilage, reducing pain and improving mobility.
3. Immune Function: Boosts immune function by improving thymus and spleen health and regulating cytokine release. It also modifies gut flora composition, enhancing overall immunity. What’s more, it may improve levels of Lactobacillus bacteria in the gut, which is great for gut health.
4. Athletic Performance: Improves athletic ability without affecting reproductive capacity.
5. Antioxidant and Anti-Inflammatory: Offers anti-aging and antioxidant benefits, protecting cells from damage.

NMN – 250mg

NMN (Nicotinamide Mononucleotide) is a molecule that boosts NAD+ levels, which is essential for cellular energy production. Here’s a bit more about NMN for longevity:

1. Boosts Energy Levels: Increases NAD+ levels, improving cellular energy production and mitochondrial function.
2. Improves Metabolism: Enhances metabolism, reduces fat accumulation, and improves glucose tolerance and insulin sensitivity. It also helps with weight loss and regulates metabolism by activating sirtuins.
3. Supports Hormone Function: NMN helps women reproduce for longer, potentially reversing menopause effects. It also regulates sleep and hormone balance.
4. Neuroprotection: Improves cognitive function, memory and focus.
5. Cardiovascular Health: Lowers blood pressure, reduces cholesterol and decreases inflammation, aiding weight loss and diabetes prevention.
6. Promotes Hair Growth: Reverses hair follicle atrophy, reduces inflammation and increases blood flow to the scalp.
7. EnhancesExercise Performance: Boosts endurance, exercise performance and overall vitality.
8. Improves Longevity: Lengthens telomeres, potentially extending lifespan as shown in studies with mice and humans aged 45 to 60.

Further Reading: How NMN May Help With Menopause

Citrusvel® Citrus Bioflavonoids Complex - 100mg

Citrusvel® contains HPMF™, an ingredient in citrus that helps boost metabolism, regulate physiology and boost your health, without drawing concerns of hepatotoxicity like red rice. Here’s why it’s in Protocol X:

1. Cardiovascular Protection: Citrus flavonoids help reduce the risk of cardiovascular diseases by blocking harmful cholesterol (oxLDL) uptake in cells.
2. Inflammation Reduction: Flavonoids lower inflammation, a key factor in atherosclerosis.
3. Cholesterol Management: They promote cholesterol efflux (removal from cells), lowering lipid buildup in arteries, which prevents heart disease.
4. Improved Bioavailability: Methylated flavonoids (PMFs) are more easily absorbed by the body and more effective in reducing inflammation, obesity and cholesterol.

Who Should Take Protocol X?

Protocol X is designed to support a wide range of health benefits, making it suitable for older adults, athletes, those with metabolic or cardiovascular concerns, individuals focused on longevity, cognitive and mental health, skin, hair and joint health, and immune support.

The blend of ingredients addresses various aspects of aging, energy production, cognitive function and overall well-being, providing a comprehensive approach to enhancing health and extending lifespan.

Read more about who Protocol X will benefit  here!

End Note

Protocol X is intended as a supplement to help supplement your healthy diet, exercise, sleep and relaxation habits, helping you to improve your health span from within.

Speak with your doctor before adding any supplement to your longevity stack to ensure it won’t interfere with any medical conditions you have or medications you’re taking.

Are you looking for more of the best longevity supplements? Try out the other supplements from our health nutrition store, including Calcium AKG, Pure NMN and Spermidine supplements. These three are included in Protocol X, but you may find taking individual ingredients suits your longevity targets more — it’s totally up to you!