Blogs

Potential Reported Side Effects of Supplements

The supplement industry has seen remarkable growth in recent years, with a wide range of products promising various health benefits. It's crucial to understand that not all supplements are without risks. In this post, we'll discuss the current Xandro Lab supplements available, as well as the potential side effects of each one. Plus, we’ll offer some tips for how to prevent side effects from supplements, so you’re well-informed before adding any to your routine.

Curcumin

One of our food supplement vitamins that’s made with BCM-95®, a patented form of curcumin that is highly absorbable.

Potential curcumin side effects: Yellowing skin or eyes, dark urine, nausea, vomiting, unusual tiredness, weakness, stomach or abdominal pain, loss of appetite.

How to combat it:

• Begin with a low dosage and gradually increase it every few days. This allows your body to acclimatise to curcumin and minimises the likelihood of adverse reactions.
• Don’t take curcumin supplements if you have or have had liver problems.
• Don’t take with blood-thinning medication,
• Curcumin may interact with certain medications, particularly blood thinners, such as warfarin (Coumadin), clopidogrel (Plavix) and aspirin, and drugs that affect blood sugar levels.
• Check the ingredients of the curcumin supplement you’re taking, as some manufacturers add ingredients that may be toxic, as well as fillers like cassava starch or barley, wheat or rye flour which can cause adverse effects in people with gluten intolerance or coeliac disease.
• Purchase from brands with high-quality standards in manufacturing and rigorous testing so you know you’re buying high-quality curcumin supplements.
• While most formulations are supported by the addition of Bioperine and pepper to enhance absorption, Xandro Lab’s BCM-95® Turmeric Curcumin does not need these additions, so it’s naturally more bioavailable and provides 8+ hours of absorption. This helps if your body doesn’t react well with Bioperine.
• Taking curcumin on an empty stomach may increase the risk of gastrointestinal discomfort. Take it with a meal or some healthy fats to enhance absorption.
• While rare, allergic reactions to curcumin can occur. Watch for signs such as rash, itching, swelling, or difficulty breathing. Seek immediate medical attention if any of these symptoms arise.
• Excessive amounts of curcumin can lead to digestive issues, such as diarrhea or nausea. Stick to the recommended dosage on the product label or follow your healthcare provider's advice.
• Before starting any new supplement regimen, especially if you have pre-existing health conditions, consult with a healthcare professional. They can provide personalised guidance based on your specific health needs.

Grab Xandro Lab’s BCM-95® Turmeric Curcumin today.

Magnesium Glycinate

Magnesium glycinate is a popular form of magnesium, that combines magnesium and the amino acid, glycine, and is known for its high absorption rate and low risk of side effects.

Potential magnesium glycinate side effects: Upset stomach,diarrhoea, nausea, vomiting and, rarely, irregular heartbeat, low blood pressure, confusion, slowed breathing, coma and cardiac arrest.

How to combat it:

• Begin with lower doses, then raise this every few days. This allows your body to adjust and reduces the risk of digestive discomfort or other side effects.

• Don’t take magnesium glycinate supplements if you are using bisphosphonates (used to treat osteoporosis), blood pressure medication or antibiotics, muscle relaxants, water pills, medications that slow blood clotting, digoxin, medications for diabetes, antacids, gabapentin, ketamine and sevelamer, or if you have a heart or kidney problems. Be sure to talk to your doctor if this is you.
• Don’t take with extremely high doses of zinc.
• Always check the amount of elemental magnesium present and purchase from reputable sources.
• Choose a reputable brand known for producing high-quality magnesium glycinate supplements. Look for products that have undergone third-party testing for purity and potency.
• Stick to the recommended dosage on the product label or as advised by your doctor. Avoid exceeding the suggested amount, as this can increase the risk of magnesium supplement side effects.
• To enhance absorption and reduce the risk of digestive upset, take magnesium glycinate with a meal or a snack. This can also help spread out the absorption over time.
• If you're taking multiple supplements, consider spreading them out throughout the day. This can help prevent interactions and allow your body to absorb each supplement effectively.
• Ensure you're well-hydrated when taking magnesium glycinate. Adequate hydration supports the body's natural processes and can help minimise the risk of side effects.

Start biohacking and check out Xandro Lab’s Magnesium Glycinate.

Spermidine

A natural polyamine that’s easily absorbed into the body and which is a powerful antioxidant and anti-inflammatory.

Potential spermidine side effects: No major side effects as it’s well-tolerated to take in all forms.

How to combat it:

• While there are no known side effects, it’s best to take spermidine supplements that are from reputable manufacturers as well as those that use extract from spermidine food sources to be safe.
• Start with a low dose and then slowly increase this every few days.
• Use a supplement log to monitor the supplements you’re taking and determine if they interact with each other or are causing adverse side effects.
• Start taking spermidine with food, then slowly start taking it on an empty stomach, as this enhances its weight-loss benefits through autophagy. If you’re not focused on this benefit, take it with food.
• Choose a reputable brand that has undergone third-party testing.
• Stick to the recommended dosage on the product label.
• Speak with your doctor before taking any new supplements.

See how Xandro Lab’s Spermidine can benefit you.

Ashwagandha

Made with Shoden®, a patented form of ashwagandha that is highly bioavailable. It’s a powerful adaptogenic herb.

Potential ashwagandha side effects: upset stomach, diarrhoea, vomiting, drowsiness and, rarely, liver problems.

How to combat it:

• Has an extensive history of safe usage, but consider taking lower amounts of ashwagandha to reduce side effects.
• Women who are pregnant should not take ashwagandha supplements, as they may increase the risk of miscarriage.
• Don’t use when taking glucose-lowering drugs, medications for high blood pressure, drugs that suppress the immune system, medications used to help with sleep or thyroid hormones.
• Start taking ashwagandha in small doses, then gradually increase this every few days until you reach your desired dosage.
• Not all ashwagandha is created equally, so choose certified supplements that are third-party tested.
• Speak with your healthcare professional before taking ashwagandha supplements.
• To enhance absorption and reduce the risk of digestive upset, take ashwagandha with a meal or a snack. This can also help spread out the absorption over time.

Supercharge stress-relief with Xandro Lab Shoden® Ashwagandha today.

Calcium AKG

A stable form of alpha-ketoglutarate that’s produced during the Krebs cycle.

Potential side effects: No significant side effects caused by alpha-ketoglutarate. The calcium may cause gas, constipation and bloating.

How to combat it:

• There are currently no known significant concerns or interactions with taking calcium AKG and other supplements/medications.
• If you do experience any adverse effects, stop taking it immediately.
• If you are pregnant or breastfeeding or have a medical condition, speak with your medical professional before using.
• Before adding Calcium AKG to your supplement routine, have a chat with your doctor.
• If you’re worried about potential side effects, try taking a lower dosage and then gradually increasing it to allow your body to get used to Calcium AKG.
• Stick to the recommended dosage on the product label or as discussed with your general practitioner.
• While Calcium AKG can be taken with or without food, try taking it on a full stomach, such as after breakfast or lunch, to prevent any stomach upset.
• Take Calcium AKG with water and keep hydrated.
• As with any supplement, make sure you choose reputable brands that are GMO-certified and whose supplements are third-party tested, like Xandro Lab.

Get your hands on a bottle of Xandro Lab’s Calcium AKG today.

NMN

Used to create NAD+, which is needed for energy metabolism, DNA repair and gene expression.

Potential NMN side effects: Possible side effects include abdominal pain, nausea, diarrhoea, gas and upper respiratory health issues.

How to combat it:

• Take the recommended dosage of up to 1,200mg per day.
• Make sure you’re taking pure NMN supplements to reduce safety concerns.
• Speak with your healthcare professional before taking any new supplement.
• Start with a low dosage, then gradually increase this.
• Choose a high-quality NMN supplement from a reputable brand.
• While it can be taken with or without food, NMN powders are often recommended to be taken in the morning, about an hour before breakfast, taken with water, or consumed directly under the tongue.
• While NMN powder is not known to interact with any medications, some supplements can contain other ingredients, like herbs, which may interact with common medications. Check the purity of the product before purchasing. Xandro Lab’s supplement is 100% Pure NMN Powder with no added ingredients.

Check out if Xandro Lab’s Pure NMN Powder is right for you.

Trans-Resveratrol

An antioxidant, anti-inflammatory and anti-aging agent with immense longevity benefits.

Potential trans-resveratrol side effects: diarrhoea, hypersensitivity, nausea, fatigue and anal pruritus.

How to combat it:

• Consider taking lower doses of resveratrol supplements or even eating foods naturally containing resveratrol.
• In certain conditions, resveratrol might act like estrogen, so if you have a condition made worse by estrogen, don’t take it.
• Don't take trans-resveratrol supplements after surgery, as they may increase the risk of bleeding.
• Medications altered by the liver also interact with resveratrol.
• Inform your doctors about your intention to take NMN Powder, so that they can determine if it will have any interactions with the medication you’re taking.
• Only purchase supplements from reputable brands of which you’re sure the supplements are pure and third-party tested for quality.
• To enhance absorption and reduce the risk of digestive upset, take Trans-Resveratrol with a meal or a snack or shortly before a meal.
• If you're taking multiple supplements, consider spreading them out throughout the day to help prevent interactions and allow your body to absorb each supplement effectively, unless they’re best taken at certain times.
• Stay hydrated to help prevent stomach and bowel discomfort.

Check out Xandro Lab’s Trans-Resveratrol Supplements today.

Make sure to speak with a medical professional, such as a doctor, before incorporating any supplements into your diet. While doctors generally aren’t specialised in longevity and may not know of all the benefits and side effects of supplements, they will be able to inform you of any potential interactions between any medications you’re taking and the supplement you’re looking to start taking.

Stay updated on the latest research and recommendations regarding the supplements you’re taking. New studies may provide insights into optimal dosages and potential interactions.

Remember, responsible use of any of these supplements can lead to significant health benefits. By following these guidelines and consulting with a healthcare provider, you can enjoy the advantages of supplements while minimising the risk of side effects.

Also, it’s important to note that supplements work best alongside healthy lifestyle choices, such as food, exercise and sleep.

If you’re interested in a range of other longevity and cognitive health supplements to improve your aging, be sure to read our posts on Longevity Supplements and Nootropics Supplements. Each supplement mentioned will explain its recommended dosage and potential side effects to keep you informed before you purchase it.

Check out Xandro Lab’s blog and research page for detailed information about the science behind the benefits of each product.