Spermidine 10 mg Spermidine 10 mg
Spermidine 10 mg Spermidine 10 mg
Spermidine 10 mg Spermidine 10 mg
Spermidine 10 mg Spermidine 10 mg
Spermidine 10 mg Spermidine 10 mg
Spermidine 10 mg
Spermidine 10 mg
Spermidine 10 mg
Spermidine 10 mg
Spermidine 10 mg
Spermidine 10 mg Spermidine 10 mg
Spermidine 10 mg Spermidine 10 mg
Spermidine 10 mg Spermidine 10 mg
Spermidine 10 mg Spermidine 10 mg
Spermidine 10 mg Spermidine 10 mg

Spermidine 10 mg

The only autophagy inducer besides 96-hour fasting. Promote cell renewal and regeneration. 99% Pure.

(220)

Key benefits

✦ Activates autophagy, the body's natural cellular renewal process
✦ Clinically shown to increase active hair follicles by over 50% in 90 days
✦ Supports cognitive performance as part of healthy aging

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Description

Spermidine is a naturally occurring polyamine that activates autophagy, the process your cells use to clear out damaged components and renew themselves, the same pathway triggered by extended fasting.

In a randomized, placebo-controlled trial (Rinaldi et al., 2017, published in Dermatology Practical & Conceptual), supplementation increased active hair follicles by over 50% in 90 days, while the placebo group saw a 20% decline. Spermidine levels decline naturally with age, which is where supplementation comes in.

Above 99% purity, manufactured in a GMP-certified facility, third-party tested.

If pregnant, nursing, or on medication, consult a physician before use.

Spermidine 10 mg

THE DIFFERENCE YOU'LL NOTICE

Thicker, healthier-looking hair

More active hair follicles over time; most people notice by month three.

Steadier energy

Support for the cellular renewal process that keeps energy from flagging as you age.

Clearer thinking

Support for cognitive performance as part of healthy aging.

Thicker, healthier-looking hair

More active hair follicles over time; most people notice by month three.

Steadier energy

Support for the cellular renewal process that keeps energy from flagging as you age.

Clearer thinking

Support for cognitive performance as part of healthy aging.

GMP, HACCP, Gluten-free, Non-GMO, GRAS, Natural ingredients, No artificial colors, No artificial fragrance, Alcohol-free, Phosphate-free, and Vegan

XANDRO QUALITY ASSURANCE

Third Party Tested

XANDRO products undergo thid-party testing for every batch produced. In addition, we continuously test for stability through the year.

GMP-CERTIFIED, HACCP-CERTIFIED, THIRD-PARTY TESTED, DEVELOPED IN SINGAPORE, NON-GMO, DAIRY-FREE, GLUTEN-FREE, ADDITIVE-FREE, and VEGAN

THE SCIENCE

The Evidence So Far

Spermidine solves one problem: as natural spermidine levels decline with age, so does autophagy, the cellular process that clears out damaged components and renews cells. Fasting is the other known trigger for this pathway, spermidine offers a dietary route to the same mechanism.

In a randomized, placebo-controlled trial, 90 days of supplementation increased active hair follicles by over 50%, while the placebo group saw a 20% decline (Rinaldi et al., 2017, Dermatology Practical & Conceptual).

In older adults with subjective cognitive decline, three months of spermidine supplementation was associated with improved cognitive performance, while the lower-intake comparison group showed continued decline (Schwarz et al., 2022, JAMA Network Open). Higher dietary polyamine intake has also been linked to reduced cardiovascular mortality in a UK Biobank cohort study (Han et al., 2024).

Why does cellular renewal slow down?

Autophagy

Spermidine Levels Decline With Age

Natural spermidine production drops over time, slowing the cellular renewal process it drives

20%

Fewer Active Hair Follicles

Placebo groups saw active hair follicles decline by approximately 20% over 90 days (Rinaldi et al., 2017)

Cognitive Function

Cognitive Decline Without Support

Lower spermidine intake was linked to declining cognitive performance over time (Schwarz et al., 2022)

How Spermidine Works

AUTOPHAGY ACTIVATION

Triggers the cellular renewal process your body uses to clear out damaged components, the same pathway activated by extended fasting.

HAIR FOLLICLE SUPPORT

Clinically shown to increase active hair follicles by over 50% in 90 days.

COGNITIVE PROTECTION

Associated with improved cognitive performance in older adults compared to lower intake.

Xandro Spermidine vs Others

Xandro Spermidine vs Others

Recommended

Spermidine 10 mg

Recommended

Other Spermidine Supplements

  • PURITY

  • DOSE PER CAPSULE

  • THIRD-PARTY TESTED

  • GMP-CERTIFIED FACILITY

PURITY

Above 99%, verified

DOSE PER CAPSULE

10mg

THIRD-PARTY TESTED

Yes, COA publicly available

GMP-CERTIFIED FACILITY

Yes

PURITY

Often unverified, purity varies widely across the market

DOSE PER CAPSULE

Often lower, 1–5mg

THIRD-PARTY TESTED

Often not disclosed

GMP-CERTIFIED FACILITY

Varies

Customers praised this supplement for boosting energy, improving hair growth, and strengthening nails. Many reported "hair growing stronger," enhanced focus, and reduced fatigue. Some noted benefits for immunity, metabolism, and overall vitality. A few customers saw no noticeable effects after a month. Fast delivery and quality were consistently highlighted.

  • My hair is growing stronger and my nails are less brittle.
  • My energy level did improve so I'm going to take this long term now
  • My hair grows faster than before. It also looks denser and fuller.
Nails (positive)Quality (positive)Delivery (positive)Hair (positive)Focus (positive)
  • 5 stars: 201 (91%)
  • 4 stars: 13 (6%)
  • 3 stars: 6 (3%)
  • 2 stars: 0 (0%)
  • 1 star: 0 (0%)
P
Peekaboo0939
Able to focus better

Bought 1 bottle to try first and found that it does help to provide more energy and am able to focus better. Going to keep taking this to see the long term benefits

P
Peekaboo0939
Energy level did improve

This is a rebuy after I bought 1 bottle to try. I found that my energy level did improve so I'm going to take this long term now

M
Mry A.
Works well

Works well on growing hair &, finger nails! Countless purchase from Xandro

T
T*****E
My body felt stronger now

Been trying out Protocol X, Lpc neuro fir the past 10 days, my body felt stronger now, so I trust the rest of the products should be effective as well. Just took a capsule, fingers crossed

P
Ppppppp33
Good product

Noticed better energy and metabolism with Spermidine. Sedentary life is unhealthy. fast delivery too!

C
Chuyunyunn
More energy and less tired

Took it for 3 weeks more energy and less tired. Improve overall health. Improve sleep and not tired when wake up. Appetite smaller too.

L
Liebep81
My friend like it

Repeat order. Bought for a friend, she likes it and finds it useful.

P
Peppawes
High quality product

Been taking this for a couple months now for autophagy, observed faster hair growth and overall feel better. High quality product, good local brand.

F
Fkokh
Seeing hair growing

Second buy. Seeing hair growing more and denser. Can google and read up benefits of Spermidine

J
Jdpinto
High recommend product

Fast delivery and good quality supplements, worth the value and quality. High recommend product. Worth the price and value

O
Otyeung2020
Repeated purchase

Great product, it is my repeated purchase

E
Eric C.
Hope it helps

Hope got use and can help with my health problems , pray pray pray

O
Otyeung2020
Fast delivery

Delivery is fast, this time the product is put in packed paper box. Nothing wrong with that but it is for my own consumption only not for gift no need for packing, I recommend seller to simply use bubble to wrap the product and reduce price, Because I immediately throw away the packaging it is not environmental friendly to be honest.

P
Ppppppp33
Nice packaging

Hope it is as good as it says. Will continue to support local if good. nice packaging.

m
mikester1891
Fantastic product

Energy level:good. Hair & Nail growth:good. Fantastic product. Fast and good delivery. Will continue to support and buy more. This is a return purchase and I will often order it every time. Delivery is on point and accurate. Thanks Xandro.

f
frostdan
Feel stronger

Noticeably better energy throughout the day with no jitters. I feel less fatigued and recover better after work. Hair and nails seem to be growing slightly faster and feel stronger after taking it consistently. Easy to swallow, no stomach discomfort or side effects. Suitable for daily use. Ive been taking this Spermidine Trihydrochloride supplement consistently for a few weeks and am satisfied with the results. It is easy to take, well packaged, and offers good value for money. While I understand the long-term anti-ageing and cellular health benefits require continued use, Ive already noticed improvements in my energy levels and overall well-being. Delivery was fast, and the seller packed the product securely. Will continue using it and would recommend it to anyone looking for a quality spermidine supplement.

L
Liewlilian332
Hair is growing stronger

My hair is growing stronger and my nails are less brittle.

L
Limszebin
Nails grow faster

suits me. improved focus. nails grow faster

M
Meow. o.
So far so good

Bought on behalf, heard that there's a lot of benefits of this supplement. So far so good.

W
Whkmay
Quick delivery

Very quick delivery, received the very next day. Bought because of good reviews, hope it helps.

L
Lfi35 S.
General protection

Have trust in Xandro products. Buying this for immunity and general protection.

A
Angrybirdy007
More energy

My intermittent fasting has improved. Energy:i have more energy. Buy it and test it for yourself

B
Ben. t.
Look promising

New to this brand. Look promising and good. Very excited to try soon. Will be back for more. Thanks seller.

J
Jotheniceman1
Increased rate of hair growth

Hair Growth:yes, there's evidence of increased rate of hair growth. more so for my post-op wound healing. Energy:more or less, have noticed lesser fatigue for more than 6 hours. Spermidine helps to mildly suppress my appetite too

E
Earth W.
Hair growing well

All my nails & hair growing well and strong !! Love it

C
Carrot. b.
Repeat purchase

Very fast delivery service. Repeat purchase for this item. Thank you.

J
Jdpinto
Good quality product

Fast delivery and good quality product for the family. Highly recommended product for the house hold.

J
Joeheng537
Feel younger

Boost it up your energy, feel younger for my own experience for consumer almost 27 months can feel healthier than last 2 years. Try a lot of supplement still XANDRO can make it.

S
Simjayson
My hair and nail grow faster

Good !! My hair and nail grow faster and stronger !!

GMP, HACCP, Gluten-free, Non-GMO, GRAS, Natural ingredients, No artificial colors, No artificial fragrance, Alcohol-free, Phosphate-free, and Vegan

EVIDENCE MATTERS

Explore the current available evidence from the XANDRO science desk

EXPLORE SCIENCE

GMP, HACCP, Gluten-free, Non-GMO, GRAS, Natural ingredients, No artificial colors, No artificial fragrance, Alcohol-free, Phosphate-free, and Vegan